Data show that miR-7 inhibits the effects of TLR9 signaling on lung cancer cells through regulation of the PIK3R3/Akt pathway.

data suggested that miR-7 mediated small cell lung cancer chemoresistance by repressing MRP1/ABCC1

these results confirm that BVP effectively inhibits non-small cell lung cancer ( NSCLC)proliferation and that miR-7, as a novel target, is likely involved in BVP-induced growth suppression and the apoptosis of NSCLC cells

Our finding for the first time demonstrates that low miR-7 expression may be an independent poor prognostic factor and targeting miR-7 may be a potential strategy for the reversal of prognosis cisplatin (CDDP) resistance in lung adenocarcinoma (LA).

the non-small cell lung cancer (NSCLC) cells within miR-7 + RELA group were observed with superior proliferative, migratory and invasive capabilities than those within miR-7 group (P < .05), and RELA expression was also significantly modified by both ciRS-7 and miR-7 (P < .05). In conclusion, the ciRS-7/miR-7/NF-kB axis could exert pronounced impacts on the proliferation, migration, invasion and apoptosis of NSCLC cells.

MiR-7-5p suppresses tumor metastasis of non-small cell lung cancer by targeting NOVA2.