High microRNA-34b is associated with small-cell lung cancer.

fi dings show that miR-34b may play an important role in non-small cell lung cancer progression; miR-34b downregulates Met, with subsequent changes of downstream p53 and Mdm2, and inversely p53 upregulates miR-34b in a feedback loop

Epigenetic inactivation of miR-34b/c by DNA methylation has independent prognostic value in patients with early-stage lung adenocarcinoma.

miR-34a and miR-34b/c promoter hypermethylation is a frequent event in lung adenocarcinoma (LAC) occurring in 68.7% and 35.3% of tested cases respectively; low miR-34b and miR-34c expression is associated with distant metastases formation in lung adenocarcinoma

miR-34b inhibits the migration/invasion and promotes apoptosis of non-small-cell lung cancer cells by YAF2.

MiR-34b-3p represses cell proliferation, cell cycle progression and cell apoptosis in non-small-cell lung cancer (NSCLC) by targeting CDK4.