Links to all GeneRIF Items | 406999 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 25234467 (MIR217) | miR-217 suppresses tumour development in lung cancer by targeting KRAS and enhances cell sensitivity to cisplatin. |
| 29934982 (MIR217) | It was shown that LINC01614 promoted the expression of FOXP1 by inhibiting miR-217, which ultimately stimulated the development of lung adenocarcinoma. |
| 30280779 (MIR217) | MicroRNA-217 was downregulated in non-small cell lung cancer (NSCLC) tissues and negatively correlated with shorter overall survival. Further results suggest that downregulated microRNA-217 promotes the occurrence and progression of NSCLC through upregulating AKT3 via PI3K pathway. |
| 30720199 (MIR217) | HOTAIR was up-regulated and miR-217 was down-regulated in non-small cell lung cancer (NSCLC) cell lines. Silencing of HOTAIR significantly repressed cell proliferation and inhibited cell migration and invasion in H1299 and A549 cells by facilitating miR-217 expression. Bioinformatics analysis and Luciferase reporter assay confirmed that DACH1 was a target of miR-217. |
| 32572881 (MIR217) | CircABCB10 promotes the proliferation and migration of lung cancer cells through down-regulating microRNA-217 expression. |