Links to all GeneRIF Items | 406989 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 21157919 (MIR206) | Overexpression of microRNA-206 inhibits cell migration and invasion of lung cancer cells. |
| 25522678 (MIR206) | tumor-suppressive miR206 inhibited dual signaling networks activated by MET and EGFR in lung squamous cell carcinoma. |
| 26075299 (MIR206) | our study provided a miRNA-gene regulatory network in lung cancer metastasis and further demonstrated the roles of miR-206 and MET in this process, which enhances the understanding of the regulatory mechanism in lung cancer metastasis. |
| 26919096 (MIR206) | miR-206 inhibits hepatocyte growth factor-induced epithelial-mesenchymal transition and angiogenesis in lung cancer by suppressing c-Met/PI3k/Akt/mTOR signaling. |
| 27014910 (MIR206) | Data show that MET is the direct target of miR-206 in lung cancer cells. |
| 27541266 (MIR206) | Using a combination of cytokine expression profiling and miRNAs algorithms, we identified VEGFA/CCL2 and FOXO3a as direct targets of miR-1, miR-206 and miR-31, respectively. Importantly, systemic delivery of anti-VEGFA/CCL2 or pre-miR-1, pre-miR-206 and anti-miR-31 significantly inhibited tumor angiogenesis, TAMs accumulation, tumor growth and lung metastasis. |
| 27806334 (MIR206) | microRNA-206 (miR-206) decreased the angiogenic ability in non-small cell lung cancer via inhibiting the 14-3-3zeta/STAT3/HIF-1alpha/VEGF pathway. |
| 27906963 (MIR206) | Our data proved that RMRP acted as an oncogene LncRNA to promote the expression of KRAS, FMNL2 and SOX9 by inhibiting miR-206 expression in lung cancer. These data suggested that RMRP might serve as a therapeutic target in lung adenocarcinoma |
| 28005074 (MIR206) | miR-206 and miR-140, as tumor suppressors, induced lung adenocarcinoma cell death and inhibited cell proliferation by modifying oncogenic TRIB2 promoter activity through p-Smad3. |
| 29664235 (MIR206) | Mir-206 role in overcoming HGF-induced gefitinib resistance in EGFR mutant lung cancer cell. Mir-206 inhibits epithelial-mesenchymal transition in the lung cancer cells through inhibition of c-Met signaling. |
| 31121484 (MIR206) | SNHG14 confers gefitinib resistance in non-small cell lung cancer by regulating miR-206-3p/ABCB1 pathway. |
| 31507089 (MIR206) | Reciprocal regulation of miR-206 and IL-6/STAT3 pathway mediates IL6-induced gefitinib resistance in EGFR-mutant lung cancer cells. |
| 31742336 (MIR206) | miR-206 regulates non-small-cell lung cancer cell aerobic glycolysis by targeting hexokinase 2. |
| 32206066 (MIR206) | MiR-206 may suppress non-small lung cancer metastasis by targeting CORO1C. |