miR-204 binds to the SIX1 3'-UTR and regulates invasion in vitro. miR-204 expression was decreased in lung cancer tissues.

Results suggest that the decreased expression of micrRNA miR-204 in plasma is a biomarker for the detection of non-small cell lung cancer (NSCLC) and the prediction of poor survival in patients with the disease.

miR-204 may act as a tumor suppressor by directly targeting ATF2 in non-small cell lung cancer

our findings revealed that miR-204 functions as a tumor suppressor in non-small-cell lung carcinoma (NSCLC) by targeting JAK2, and that miR-204 may therefore serve as a biomarker for the diagnosis and treatment of NSCLC.

Notably, sirtuin 1 was recognized as a direct downstream target of microRNA-204 in HepG2 cells. Moreover, si-SIRT1 significantly inhibited cell invasion and migration process.his study reveals a novel mechanism by which MALAT1 stimulates hepatocellular carcinoma progression and justifies targeting metastasis-associated lung adenocarcinoma transcript 1 as a potential therapy for hepatocellular carcinoma.

Study revealed that miR- 204 acted as a potent lung tumor suppressor in lung cancer by targeting the FZD4:rs713065 C allele, therefore inhibiting FZD4 expression and cellular function in the Wnt-signaling-driven tumor progression.

Mir-204 attenuates angiogenesis in lung adenocarcinoma via JAK2-STAT3 pathway.

these results indicated that miR204 regulates the proliferative, migratory and invasive capabilities of lung cancer cells by targeting PCNA1.

MiR-204 inhibited cell metastasis and epithelial-mesenchymal transition in lung adenocarcinoma through targeting SOX4.

The study demonstrated that LINC00483 facilitates the proliferation, migration and invasion of lung adenocarcinoma cells by acting as a sponge for miR-204-3p, which in turn regulates ETS1.

LncRNA AWPPH accelerates the progression of non-small cell lung cancer by sponging miRNA-204 to upregulate CDK6.