Links to all GeneRIF Items | 406951 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 25435430 (MIR16-2) | The miR-16 directly targeted anti-apoptotic protein Bcl-2 in paclitaxel resistant lung cancer cells |
| 29138833 (MIR16-2) | Results revealed that miR-16 was significantly downregulated, and ATG3 was significantly upregulated in non-small cell lung carcinoma (NSCLC) patient tissue samples. ATG3 was found to be a direct target of miR-16. Finally, the study showed that miR-16 overexpression rescued TGF-beta1mediated inhibition of autophagy and plays important roles in the EMT of NSCLC cells. |
| 31298377 (MIR16-2) | MicroRNA-16 inhibits the proliferation, migration and invasion of non-small cell lung carcinoma cells by down-regulating matrix metalloproteinase-19 expression. |
| 31379227 (MIR16-2) | Decreased miR-16 expression may play a role in upregulating expression of MEK1 and promoting proliferation and invasion of lung cancer cells. |