Reduced expression of miR-101 was associated with overexpression of EZH2 in non-small cell lung cancer.

miR-101 DNA copy loss is a prominent subtype specific event in lung cancer.

miR-101 downregulation associates with DNMT3a overexpression in lung cancer cell lines and patient tissues.

We for the first time proposed the role interleukin-1beta-mir-101-EZH2 axes in the particle-induced lung cancer

miR-101-CXCL12 pathway is partially responsible for cancer-associated fibroblast-mediated progression of lung cancer

Results show that miR-101 expression is reduced and associated with poor prognosis in p53 WT lung adenocarcinoma patients. miR-101 is upregulated in a p53-dependent manner after exposure of cells to Pol I inhibitors, and is involved in positive-feedback regulation of p53 via repression of EG5, resulting in induction of apoptosis.