Links to all GeneRIF Items | 4017 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 24632622 (Loxl2) | Loss and gain of function analyses combined with in vivo studies in syngeneic breast cancer models demonstrate the participation of LOXL2 and E47 in tumor growth and their requirement for lung metastasis. |
| 21519871 (LOXL2) | Down-regulation of lysyl oxidase-like 2 is associated with disease progression in lung adenocarcinomas. |
| 26676674 (LOXL2) | Loss of tumor-suppressive miR29s enhanced cancer cell invasion in lung SCC through direct regulation of oncogenic LOXL2. |
| 27488440 (LOXL2) | Overexpression of LOXL2 and SERPINH1 was observed in clinical specimens of lung cancer and fibrotic lesions. Downregulation of miR-29a caused overexpression of LOXL2 and SERPINH1 in lung cancer and IPF, suggesting that these genes are involved in the pathogenesis of these two diseases. |