lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

3897

PubMed (Gene Name)

Literature evidence

21860410 (L1CAM)

inhibition of HIF-1 activity in BrCa cells inhibits primary tumor growth and metastasis of BrCa cells to the lungs by blocking expression of angiopoietin-like 4 (ANGPTL4) and L1 cell adhesion molecule (L1CAM);ANGPTL4 inhibits endothelial cell(EC)-EC interaction; L1CAM increases the adherence of BrCa cells to ECs

21985405 (L1CAM)

L1CAM is a novel prognostic marker for non small cell lung cancer cells that is upregulated by epithelial mesenchymal transition induction and appears to be instrumental for enhanced cell invasion

22307136 (L1CAM)

Data suggest that targeted inhibition of L1CAM may be a novel therapy for non-small cell lung cancer (NSCLC).