lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

3880

PubMed (Gene Name)

Literature evidence

16324274 (KRT19)

CEA and CK19 expression was higher in lung cancer patients than in patients with benign lung diseases and healthy controls.

17450257 (KRT19)

In conclusion, CYFRA 21-1 is a useful tumor marker before and after surgical treatment in lung cancer.

17697728 (KRT19)

serum Sialyl Lewisx and cytokeratin 19 fragment were prognostic markers for stage I non-small cell lung cancer

18080980 (KRT19)

Our results suggest that the degree of cytokeratin 19 expression could be a new prognostic factor in non-small cell lung cancer.

18329483 (KRT19)

This preliminary study provides evidence that the CK19/EpCAM2 and/or CK19/P-cadherin ratio(s) may be a simple and accurate prognostic indicator of clinical outcome in early-stage adenocarcinoma of the lung.

18394347 (KRT19)

The levels of CYFRA21-1 in pleural effusion of patients with lung cancer were much higher than those with benign lung disease.

18571761 (KRT19)

Nucleosomes and CYFRA 21-1 have roles in tumor response to chemotherapy in recurrent non-small cell lung cancer

20350214 (KRT19)

Combining CEA with Cyfra 21-1 analysis of malignant pleural effusion increases diagnostic sensitivity of lung adenocarcinomato nearly 100%

20398190 (KRT19)

the expression of Cytokeratins 7, 8, 18, and 19 may serve as differential diagnostic markers for pulmonary large cell neuroendocrine carcinoma and small cell lung carcinoma

21397974 (KRT19)

preoperative expression level is a prognostic factor in patients with stage I non-small cell lung cancer

22088515 (KRT19)

SCC, CEA, Cyfra 21-1 and NSE are valuable in the early diagnosis of lung cancer among suspicious nodules in the lung, especially when they were assayed together for one patient.

23352032 (KRT19)

Results indicate that CEA and CYFRA 21-1 are reliable serum tumor markers for the diagnosis of lung cancer.

23408492 (KRT19)

High CYFRA 21-1 expression is associated with lung adenocarcinoma-associated cytologically negative pleural effusions.

23591159 (KRT19)

High CYFRA 21-1 levels are associated with response to epidermal growth factor receptor-tyrosine kinase inhibitor therapy in non-small-cell lung cancer harboring EGFR mutation.

23810363 (KRT19)

High CK19 mRNA expression correlated with lung cancer stage and distant metastases.

23879483 (KRT19)

serum CYFRA 21-1 valuesmay be a potential independent prognostic factor in patients with advanced lung adenocarcinoma.

23886796 (KRT19)

upregulated transcription correlates with tumor size in Non-Small-Cell lung cancer

23909079 (KRT19)

The combination of weak CK19 expression and high serum CYFRA21-1 levels is a predictor of poorer prognosis for patients with human lung sqamous cell carcinoma.

23992005 (KRT19)

High serum CYFRA21-1 expression is associated with lung cancer

25503147 (KRT19)

The expression of CK19 tended to be positively correlated with the expression of FOXP3. High expression of FOXP3 in regional lymph nodes was a significant unfavorable prognostic factor in patients with stage I non-small cell lung cancer.

26163610 (KRT19)

Elevation of serum CYFRA21-1 is associated with Non-small Cell lung cancer.

26880855 (KRT19)

Results show that serum miR21 could serve as an important marker for auxiliary diagnosis of early non-small cell lung cancer (NSCLC), while joint detection of serums miR21 and CYFRA21-1 levels could improve diagnostic efficiency.

26979333 (KRT19)

The cytologic tumor marker c-CYFRA was positively associated with EGFR mutations in non-small cell lung cancer (NSCLC). EGFR mutation-positive NSCLCs have relatively lower glycolysis compared with NSCLCs without EGFR mutation

27072222 (KRT19)

Significant levels of CEA, CYFRA 21-1, NSE, and TSGF were detected in the serum. The amounts found were useful for diagnosing non-small cell lung cancer (NSCLC) patients who depended on the currently limited biomarker development.

27072263 (KRT19)

BALF and serum NSE, CEA, and CYFRA21.1 elevated in lung cancer, which had prompt value for pathology, especially significant for BALF.

28982900 (KRT19)

Serum CYFRA 21-1 level may be a predictive factor for patients with non-small cell lung cancers treated with EGFR-TKIs, regardless of EGFR mutation status.

29247745 (KRT19)

The detection of TK1 combined with that of cytokeratin-19 fragment (CYFRA21-1), CEA or NSE increased the diagnostic value of TK1 for lung squamous cell carcinoma, adenocarcinoma and small cell lung cancer, respectively.

30885344 (KRT19)

serial measurements of serum CYFRA 21-1 levels could provide a valuable method for follow-up monitoring of patients with adenocarcinoma of the lung to detect recurrence

31450896 (KRT19)

High CK19 expression is associated with Non-Small-Cell lung Carcinoma.

32519739 (KRT19)

KRT8 and KRT19, associated with EMT, are hypomethylated and overexpressed in lung adenocarcinoma and link to unfavorable prognosis.