Links to all GeneRIF Items | 3725 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 16158054 (JUN) | Dysregulated c-jun expression may be involved in the acquisition of anchorage independence in the process of human lung carcinogenesis |
| 19018257 (JUN) | AP-1 and PI3K/Akt pathways play an essential role in the growth of somenon-small cell lung cancer cells |
| 20331627 (JUN) | decrease of lung cancer cell proliferation by ZAK may involve the ERK and JNK pathways via an AP-1 transcription factor. |
| 21081043 (JUN) | The expression of COX-2 was significantly associated with the expressions of transcription factors NFAT3 and c-Fos in nonsmall cell lung cancer. |
| 21972703 (JUN) | The increased levels of ICAM-1 and C-Jun are negative prognostic factors for the patients with non-small cell lung cancer. |
| 22189957 (JUN) | Genetic variants of c-Jun and their interaction with smoking and drinking increase the susceptibility to lung cancer. |
| 22438909 (JUN) | Blimp1 is a mediator of Ras/Raf/AP-1 signaling that promotes cell migration, and is repressed by LOX-PP in lung cancer. |
| 23182717 (JUN) | Data show that a photodynamic therapy (PDT) dose-dependent upregulation of CRP gene, as well as of PTX3 and ficolin 1 genes in lung tumor A549 cells, and indicate critical role played by PI3K/Akt/AP-1 pathway. |
| 27424491 (JUN) | This is the first study to show how TGF-beta regulates the expression of Claudin-4 through c-Jun signaling and how this pathway contributes to the migratory and tumorigenic phenotype of lung tumor cells. |
| 28566434 (JUN) | These findings suggest that increased JUN expression and activity may contribute to gefitinib resistance in non-small cell lung cancer. |
| 28618937 (JUN) | Our results suggest that hypoxia-elicited c-Jun/activator protein 1 regulates 37-kDa laminin receptor precursor expression, which modulates migration and invasion of lung adenocarcinoma cells. |
| 29362431 (JUN) | transcription factor c-Jun bound to the promoter region of human miR-374a and suppressed miR-374a in A549 and pc-9 cells while inducing it in SPCA-1 and H1975 cells. Increased levels of miR-374a appeared to serve a protective role by targeting CCND1 in early-stage non-small-cell lung cancer. |
| 32950569 (JUN) | AMOTL2 inhibits JUN Thr239 dephosphorylation by binding PPP2R2A to suppress the proliferation in non-small cell lung cancer cells. |
| 20716630 (Jun) | TAM67 (mutant of c-jun) decreased tumor number and overall lung tumor burden in chemically induced mouse lung tumor models. |