lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

3673

PubMed (Gene Name)

Literature evidence

11775028 (ITGA2)

Bromodeoxyuridine induces integrin expression at transcriptional (alpha2 subunit) and post-transcriptional (beta1 subunit) levels, and alters the adhesive properties of two human lung tumour cell lines.

23951036 (ITGA2)

Integrin alpha2 beta1 and EGFR cooperatively promote higher invasiveness of ionizing radiation - survived lung cancer cells, mediated in part by the PI3K/Akt signaling pathway, and might serve as alternative targets in combination with radiotherapy.

27009236 (ITGA2)

Study identified a novel RANKL function in the promotion of cell adhesion to type I collagen through the RANKL-NF-kappa B-integrin alpha 2 pathway and found integrin alpha2 and RANKL up-regulated in non small cell lung carcinoma.