Links to all GeneRIF Items | 3595 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 17602269 (IL12RB2) | Epigenetic silencing of IL-12Rbeta2 is a frequent event in lung cancers. Aberrant methylation of this gene seems to be a useful predictor of long-term outcome for adenocarcinoma of the lung. |
| 25695486 (IL12RB2) | Estrogen receptor beta 2 regulates IL12RB2 expression via p38 MAPK signaling and inhibits non-small-cell lung cancer proliferation and invasion. |
| 26547104 (IL12RB2) | IL12RB2 polymorphisms correlate with risk of lung adenocarcinoma. |
| 29956791 (IL12RB2) | The Cox proportional hazard models revealed that IL12Rb2 and p38MAPK predicted a long OS. To the best of our knowledge, the present study is the first to reveal a close association between IL12Rb2 and p38MAPK, and their possible function in nonsmall cell lung cancer progression |