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Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

3553

PubMed (Gene Name)

Literature evidence

12077278 (IL1B)

tumors derived from a retroviral vector coding human IL-1BETA gene transduced into Lewis lung carcinoma cells secrete IL-1 beta into the tumor milieu, which promotes tumor growth through hyperneovascularization.

14961572 (IL1B)

Polymorphisms of the interleukin-1 beta gene are associated with increased risk of non-small cell lung cancer

16126303 (IL1B)

results indicate that individuals homozygous for the IL1RN*1 allele and carrying the IL1B-31T allele had increased risk of non-small cell lung cancer; findings support the significance of IL1 gene cluster polymorphisms and risk of lung cancer

20035239 (IL1B)

IL1B rs1143634 polymorphism is associated with lung cancer.

22951596 (IL1B)

a lung cancer risk haplotype in the IL1B gene regulatory region is associated with increased expression of IL1B and increased lung cancer risk

23784458 (IL1B)

Studies suggest that the interleukin 1, beta (IL1B) -31 T/C and +3954 C/T polymorphisms are associated with lung cancer risk.

25130968 (IL1B)

relationship between IL-6-643 (C/G) and IL-1beta-31 (C/T) polymorphisms and lung cancer risk among female non-smokers

25428391 (IL1B)

We for the first time proposed the role interleukin-1beta-mir-101-EZH2 axes in the particle-induced lung cancer

27320908 (IL1B)

These studies elucidate an important role for neutrophils and IL-1beta in lung carcinogenesis.

28212736 (IL1B)

TAp73beta upregulates pro-IL-1beta mRNA and processed IL-1beta protein. In addition, analysis of breast and lung cancer patient cohorts demonstrated that interaction between p73 and IL-1beta predicts a negative survival outcome in these cancers.

19842848 (Il1b)

Lack of soluble tumor necrosis factor alpha receptor 1 and 2 and interleukin-1beta compartmentalization in lungs after a single intratracheal inoculation with live Porphyromonas gingivalis.

21300825 (Il1b)

During lung metastasis, manipulation of IL-1/IL-17 may affect local inflammatory responses at tumor sites, which may result in an improved antitumor immune response and a more favorable prognosis.

27885671 (Il1b)

Before the arrival of tumor cells, the lung-recruited monocytic myeloid-derived suppressor cells produced IL-1beta, thereby increasing E-selectin expression and promoting tumor cell arrest on endothelial cells.

27935337 (Il1b)

Irradiation targeting a D2A1 tumor and its microenvironment increased the level of the inflammatory cytokine IL-1beta and was associated with the promotion of cancer cell invasion and lung metastasis development