Links to all GeneRIF Items | 355 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 12037669 (FAS) | alteration associated with nodal metastasis in non-small cell lung cancer |
| 12824926 (FAS) | increased expression of soluble Fas in pleural effusion associated with lung cancer |
| 14512182 (FAS) | Fas polymorphism is associated with altered apoptotic capacity in lymphocyte cultures, and risk of lung cancer |
| 15937082 (FAS) | FAS polymorphisms contribute to susceptibility of lung cancer. |
| 17014925 (FAS) | These results suggest that the FAS-1377G>A and -670A>G and FASL-844C>T polymorphisms do not significantly affect the susceptibility to lung cancer in Koreans. |
| 17708363 (FAS) | There was no relationship between Fas-1377 G-->A polymorphism and lung cancer |
| 19240174 (FAS) | Polymorphisms in the FAS is associated with early stage non-small cell lung cancer. |
| 21430781 (FAS) | knockdown of FAS and several components of the NF-kappaB pathway specifically enhanced cell death induced by the EGFR TKI erlotinib in EGFR-mutant lung cancer cells |
| 21466843 (FAS) | Celastrol can induce apoptosis of human non-small-cell lung cancer A549 cells through activation of both mitochondria- and Fas/FasL-mediated pathways. |
| 22821704 (FAS) | Non-small-cell lung cancer patients carrying XRCC1 Arg194Arg, FAS-1377GG, and FASL-844T allele displayed completely no response to platinum based drugs. |
| 25596086 (FAS) | FasL -844 SNP is associated with the susceptibility of pulmonary AD in age <60 years people. Fas -1377 SNP may modify the association of FasL -844 SNP with the risk of pulmonary adenocarcinoma. |
| 26823709 (FAS) | Suggest reduced membranous Fas expression as a mechanism of apoptotic resistance in non-small cell lung carcinomas. |
| 28320962 (FAS) | Study identify genes highly expressed in Kras knockout lung cancer cells, including the Fas receptor gene. Antibodies that activate Fas receptor selectively induced apoptosis in Kras-independent lung cancer cells suggesting that FAS is involved in KRAS-related drug resistance. |
| 17951400 (Fas) | Fas(-) osteosarcoma cells are selected during lung metastases formation and inhibition of Fas signaling in tumors or lack of FasL in the host environment allows the proliferation of Fas(+) osteosarcoma cells in the lungs and promotes metastases growth. |
| 19265159 (Fas) | Fas signal can promote lung cancer growth in vivo by recruiting myeloid-derived immunosuppressive cells and T regulatory cells into the tumor microenvironment via inflammatory prostaglandin E2. |