Metastasis associated in colon cancer 1 gene overexpression may be a useful marker for predicting postoperative recurrence in patients with lung adenocarcinoma after surgery.

Overexpression of MACC1 mRNA is associated with postoperative recurrence in patients with lung adenocarcinoma following surgery

Circulating MACC1 mRNA represents a potential noninvasive, diagnostic and prognostic marker for non small cell lung cancer.

H19 may regulate non-small cell lung cancer (NSCLC) metastasis through modulating cellular signaling pathway proteins related to cell proliferation and cell adhesion, including MACC1, EGFR, beta-catenin and ERK1/2.

High expression of MACC1 is associated with non-small cell lung cancer.

YB-1 promoted lung adenocarcinoma growth and progression in vitro and in vivo through directly binding to the MACC1 promoter and enhancing MACC1/c-Met pathway.

MACC1 is an independent prognostic marker in patients with small invasive lung adenocarcinoma after complete surgical resection. Differential outcomes are associated with MACC1 expression level.

MACC1 knockdown effectively inhibited cell proliferation and promoted apoptosis of lung adenocarcinoma cells by regulating the beta-catenin pathway.

Study demonstrated that the overexpression of MACC1 in carcinomaassociated fibroblasts promoted the invasive ability of lung adenocarcinoma cells via paracrine signaling.

Circ-FOXM1 upregulated the level of pancreatic progenitor cell differentiation and proliferation factor (PPDPF) and metastasis-associated in colon cancer 1 (MACC1) by sponging miR-1304-5p, thereby increasing the proliferation and invasion of non-small cell lung cancer cells.

LncRNA MACC1-AS1 Promotes lung Adenocarcinoma Cell Proliferation by Downregulating PTEN.