These findings suggest that the large size of a (GT)(n) repeat in the HO-1 gene promoter may be associated with the development of lung adenocarcinoma in Japanese male smokers.

HO-1 protein is upregulated in epithelial malignant cells in non-small cell lung cancer and its expression is associated with higher stages of the disease

HO-1 is a poor prognostic predictor and its over-expression may increase the metastatic potential of non-small cell lung cancer

Interplay between HMOX1 and miR-378 significantly modulates non-small cell lung carcinoma progression and angiogenesis.

action of thymidine phosphorylase in non-small cell lung cancer: crosstalk with Nrf2 and HO-1

this study is the first to demonstrate that HG treatment of A549 human lung epithelial cells promotes tumor cell invasion and increases metastasis-associated protein expression by up-regulating HO-1 expression via ROS or the TGF-b1/PI3K/Akt signaling

Finally, the effect of NGAL down-regulation on the growth of human lung adenocarcinoma was determined in BALB/c nude mice.

we propose that upregulation of HO1 expression by a smallmolecule activator may be effective in controlling SexHinduced cell migration in lung cancer.

Acetaminophen sensitizing erastin-induced ferroptosis via modulation of Nrf2/heme oxygenase-1 signaling pathway in non-small-cell lung cancer.

overexpression of HO-1 or HO-1G143H in normal tissues could significantly change the survival rate of tumour-bearing mice, but HO-1 overexpression could inhibit lung metastases and HO-1G143H could significantly promote lung metastases.