lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

3149

PubMed (Gene Name)

Literature evidence

23609034 (HMGB3)

HMGB3 plays an important role in non-small cell lung cancer progression.

30446524 (HMGB3)

HMGB3 has higher expression in non-small cell lung cancer tissues.HMGB3 is the target gene of miR-758.

31422060 (HMGB3)

HOTTIP was upregulated and miR-615-3p was downregulated in non-small cell lung cancer (NSCLC) tissues and cells. Hypoxia induced glycolysis, increased HOTTIP and HMGB3 mRNA levels and repressed miR-615-3p expression in NSCLC cells. HOTTIP deficiency or miR-615-3p expression restoration repressed hypoxia-induced glycolysis. HOTTIP acted as a molecular sponge for miR-615-3p and HMGB3 was a direct target of miR-615-3p.

32871048 (HMGB3)

LncRNA PITPNA-AS1 boosts the proliferation and migration of lung squamous cell carcinoma cells by recruiting TAF15 to stabilize HMGB3 mRNA.