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Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

302

PubMed (Gene Name)

Literature evidence

21132403 (ANXA2)

results suggest that annexin-1, annexin-2, and annexin-3 are identified as potential biomarkers associated with lymph node metastasis in lung adenocarcinoma

23494179 (ANXA2)

Annexin II up-regulation was associated with non-small cell lung cancer.

23529818 (ANXA2)

Elevated expression of annexin II was associated with lymph node metastatic lung cancers.

25519022 (ANXA2)

It was found that soluble ANXA2 concentration in serum samples from 42 lung cancer patients was significantly higher than that from 43 healthy individuals

28178129 (ANXA2)

expression elevated in lung squamous cell carcinoma tissue

28886730 (ANXA2)

These data suggested that Annexin A2 induces cisplatin resistance of non-small cell lung cancer (NSCLC)via regulation of JNK/c-Jun/p53 signaling, and provided an evidence that blockade of Annexin A2 could serve as a novel therapeutic approach for overcoming drug resistance in NSCLCs