lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

2931

PubMed (Gene Name)

Literature evidence

21316358 (Gsk3a)

glycogen synthase kinase 3alpha/beta (GSK3alpha/beta) modulates tumor necrosis factor-a (TNF) induced increased lung vascular permeability

25486534 (GSK3A)

Elevated GSK3 protein kinase activity is associated with non-small cell lung carcinoma

27049759 (GSK3A)

demonstrated that GSK-3alpha is regulated by CREB in lung cancer and is required for the cell viability. These findings implicate CREB-GSK-3alpha axis as a novel therapeutic target for lung cancer treatment

28662516 (GSK3A)

Using integrated analysis of genome-wide short hairpin RNA (shRNA) screening data in combination with genome-wide gene expression data, the study identified GSK3 as one of the key factors in p53-mediated apoptosis in human lung cancer cells.