Links to all GeneRIF Items | 2908 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 16806572 (NR3C1) | Glucocorticoid receptor is expressed in advanced non-small cell lung cancer |
| 17496926 (NR3C1) | A profound apoptotic effect of glucocorticoid receptor (GR) in small cell lung cancer (SCLC) cells may explain the low levels of endogenous GR in SCLC cells. |
| 20015838 (NR3C1) | GR expression is pro-apoptotic for human SCLCs (small cell lung cancers) in vivo, as well as in vitro, suggesting that loss of GR confers a survival advantage to SCLCs. |
| 21984896 (NR3C1) | These data suggest that DNA methylation decreases GR gene expression in human small cell lung cancer cells. |
| 24736075 (NR3C1) | Low glucocorticoid receptor alpha expression is associated with low response to pemetrexed in non-small-cell lung cancer. |
| 27179949 (NR3C1) | Logistic regression revealed that four variants in NR3C1 and SATB1 were significantly associated with lung cancer risk after false discovery rate (FDR) correction [For NR3C1, rs9324921: odds ratio (OR)=1.23, P for FDR=0.029; rs12521436: OR=0.85, P for FDR=0.040; rs4912913: OR=1.17, P for FDR=0.040; For SATB1, rs6808523: OR=1.33, P for FDR=0.040]. |
| 27484907 (NR3C1) | this paper shows that glutathione peroxidase 3 expression can be regulated independently via epigenetic or glucocorticoid receptor-mediated mechanisms in lung cancer cells |