lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

2736

PubMed (Gene Name)

Literature evidence

24423612 (GLI2)

Our studies demonstrate an important role for GLI2 in lung squamous cell carcinoma

25359619 (GLI2)

High Gli2 expression is associated with bone destruction in lung and breast cancer.

26762562 (GLI2)

this study shows that Gli2 expression was more often positive in advanced non-small-cell lung carcinoma patients refractory to platinum-based chemotherapy

26936993 (GLI2)

High Gli2 expression is associated with non-small cell lung cancer.

31697978 (GLI2)

Our results indicate that the miR-182-5p/GLI2 axis modulates tumorigenesis and cisplatin-resistance in lung adenocarcinoma (LADC) cells, by influencing the hedgehog signaling pathway (HHSP). Therefore, this axis might be considered as a potential biomarker and future therapeutic target in LADC patients