lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

2719

PubMed (Gene Name)

Literature evidence

11893651 (GPC3)

Candidate lung tumor suppressor gene which may be regulated by tobacco exposure.

12816733 (GPC3)

These findings suggest that GPC3 is a candidate lung tumor suppressor gene whose expression may be regulated by exposure to cigarette smoke and functions to modulate cellular response to exogenous damage.

18469798 (GPC3)

Glypican-3 expression is a potential candidate marker for early detection of lung squamous cell carcinoma.

21556932 (GPC3)

High GPC3 mRNA expression is associated with lung squamous cell carcinoma.

26345955 (GPC3)

GPC3 may be a candidate marker for detecting lung squamous cell carcinoma.

31160489 (GPC3)

the present study demonstrates that up-regulation of GPC3 accelerates the progression of lung squamous cell carcinoma (SCC) in a b-catenin-dependent manner. Our study provides a theoretical basis for GPC3/b-catenin as a novel diagnostic marker and therapeutic target for lung SCC