Links to all GeneRIF Items | 27178 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 26791086 (IL37) | Findings show IL-37 mRNA and protein expressions significantly decreased in non-small cell lung cancer and demonstrate its protective role possibly through inhibiting tumor angiogenesis. |
| 29106392 (IL37) | Low IL37 expression promotes lung tumor metastasis. |
| 29575809 (IL37) | Our results showed that IL-37 plays an inhibitory role in non-small cell lung cancer progression, possibly by suppressing STAT3 activation and decreasing epithelial-to-mesenchymal transition by inhibiting IL-6 expression. IL-37 could serve as a potential novel tumor suppressor in non-small cell lung cancer |
| 33293426 (IL37) | Targeting MARCO and IL37R on Immunosuppressive Macrophages in lung cancer Blocks Regulatory T Cells and Supports Cytotoxic Lymphocyte Function. |