Links to all GeneRIF Items | 2690 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 18299312 (GHR) | The Thr495Pro polymorphism of Growth Hormone Receptor(GHR) was associated with the risk of lung cancer in a redundant interaction with smoking and familial history of cancer. |
| 28967904 (GHR) | Study in lung cancer BEAS-2B cells shows that SOCS2 binding to the growth hormone receptor (GHR) is impaired by a GHR threonine substitution at Pro 495. This results in decreased internalisation and degradation of the receptor. |