Links to all GeneRIF Items | 2624 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 22541434 (GATA2) | Of 26 non-small cell lung cancer cell lines, 14 were KRAS mutant and 12 were wild type; short-term GATA2 knockdown led to specific decreased cell viability and increased apoptosis in KRAS mutant NSCLC cells, comparable to the effect seen with loss of KRAS itself. |
| 24807155 (GATA2) | GATA2 is epigenetically repressed in human and mouse lung tumors and its further inhibition is not a valid therapeutic strategy for KRAS mutant lung cancer. |