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Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

25970

PubMed (Gene Name)

Literature evidence

22901222 (SH2B1)

High SH2B1 expression was associated with lymph node metastasis, and recurrence in non-small cell lung cancer.

27164951 (SH2B1)

Results identified SH2B as a functional target of miR-361 which down-regulation suppresses lung cancer progression and metastasis through regulation of SH2B1.

29380446 (SH2B1)

Data reported that SH2B1 expression levels were significantly upregulated and positively associated with EMT markers and poor patient survival in lung adenocarcinoma (LADC) specimens. Further results reveal that SH2B1 has a major role in LADC progression and that SH2B1 is a critical activator of Wnt/beta-catenin signaling.