Links to all GeneRIF Items | 2539 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 24270845 (G6PD) | G6PD is the major proliferative target of TAp73 in the human lung cancer H1299 cells. |
| 26399441 (G6PD) | G6PD glycosylation is increased in human lung cancers. Glycosylation activates G6PD activity and increases glucose flux through the PPP, thereby providing precursors for nucleotide and lipid biosynthesis, and reducing equivalents for antioxidant defense. |
| 29753088 (G6PD) | G6PD expression was significantly associated with a higher pathological TNM stage (p=0.0024), lymph node metastasis (p=0.0187), poorer differentiation (p=0.0046), pleural invasion (p=0.0197), vascular invasion (p<0.0001), lymphatic invasion (p=0.0200) and poorer prognosis (p=0.0005) in lung adenocarcinoma. |