Overexpression of Dicer correlates with precancerous conditions for lung adenocarcinoma.

DICER1 mutations are associated with both familial multinodular goiter (MNG) and MNG with Sertoli-Leydig cell tumor of the ovary, independent of pleuropulmonary blastoma

germline DICER1 mutations may be found in Pleuropulmonary blastoma-associated ovarian sex cord-stromal tumors (OSCST) cases.

We report DICER1 mutations in seven additional families that manifested uterine cervix embryonal rhabdomyosarcoma , primitive neuroectodermal tumor, Wilms tumor, pulmonary sequestration and juvenile intestinal polyp.

DICER1 and DROSHA copy number variation may be an important mechanism of upregulation/downregulation of miRNAs in lung cancer

Results indicate the role of Drosha, Dicer and Ago2 proteins in the development of non-small cell lung carcinomas (NSCLC) and suggest that Dicer may be implicated in the progression of these tumors to advanced stages.

DICER1 pathogenic variation is associated with pleuropulmonary blastoma, cystic nephroma and Sertoli-Leydig cell tumor.

DICER1germline intronic mutation isa ssociated with multinodular goiter, ovarian Sertoli-Leydig cell tumor, and lung cyst.