Increased soluble VEGFR-1 level is an important parameter in lung cancers.

There was a significant positive correlation between the level of expression of VEGF and VEGF-R1 (P = 0.04) in both control groups and lung bearing tumorlets.

Prechemotherapy soluble VEGFR-1 can be helpful for prediction of long-term response to therapy in lung cancer.

Data suggest that miR-200 suppresses lung tumorigenesis by targeting Flt1.

study concludes that VEGF R1 and Tie-2 receptors may play important role in lung cancer development and their receptor concentrations may reflect the patients' response to treatment.

No significant difference of VEGFR1 levels in bronchoalveolar lavage fluid are associated between malignant and non-malignant groups in lung cancer.

This study found significant associations between a VEGFR1 polymorphism and risk of COPD or lung cancer in Chinese population.

In this study, the authors identify VEGF165, a splice variant of VEGF-A, as a regulator of sVEGFR1-i13 expression in lung carcinoma, and further show that VEGF165 cooperates with the transcription factor SOX2 and the splicing factor SRSF2 to control sVEGFR1-i13 expression.