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Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

2202

PubMed (Gene Name)

Literature evidence

17671114 (EFEMP1)

EFEMP1 is silenced by promoter hypermethylation in lung cancer

19913326 (EFEMP1)

Aberrant promoter methylation and loiss of expression in non-small cell lung carcinoma

21901248 (EFEMP1)

fibulin-3 negatively modulates the invasiveness of lung cancer cells via regulation of MMP-7 and MMP-2 and its expression is regulated by hypermethylation of the promoter region

24013232 (EFEMP1)

FBLN3 suppresses both epithelial-to-mesenchymal transition and self-renewal of lung cancer stem cells by modulating the IGF1R pathway.

24142183 (EFEMP1)

fibulin-3 negatively modulates the invasiveness of lung cancer cells via regulation of p38-MAPK and MMP-2/9.

24480807 (EFEMP1)

Downregulation of fibulin-3 is associated with lung cancer invasion.

25676403 (EFEMP1)

EFEMP1 suppresses growth and invasion of lung cancer cells by downregulating MMP7 expression.