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Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

220042

PubMed (Gene Name)

Literature evidence

26493727 (DDIAS)

DDIAS is a target of NFATc1 and is associated with cisplatin resistance in lung cancer cells.

28079882 (DDIAS)

these findings indicate that the stability of the DDIAS protein is regulated by CHIP/HSP70-mediated proteasomal degradation and that CHIP overexpression stimulates the apoptosis of lung cancer cells in response to DNA-damaging agents

29242605 (DDIAS)

High DDIAS expression suppresses TRAIL-mediated apoptosis by inhibiting DISC formation and destabilizing caspase-8 in lung and liver cancer.