lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

2191

PubMed (Gene Name)

Literature evidence

23835897 (FAP)

Elevated FAP-alpha expression may be associated with inflammation and suppressed lymphocyte-dependent immune response, which then result in the lung tumor progression.

29115573 (FAP)

These results revealed that FAPalpha promoted the growth, adhesion and migration of lung squamous cell carcinoma cells. In addition, FAPalpha regulated lung cancer cell function, potentially via the PI3K and SHH pathways. Further investigations are required to examine the role of FAPalpha in lung AC cells.