Ets-1 appears to be a useful predictor of poor prognosis after surgical resection in lung adenocarcinoma patients.

Dual specificity phosphatase 6 (DUSP6) is an ETS-regulated negative feedback mediator of oncogenic ERK signaling in lung cancer cells.

ilencing endogenous Ets1 by siRNA in mouse cell lines decreases Twist1 mRNA levels, decreases invasion, and increases cell growth. Ets1 and Twist1 are at the crossroad of several signaling pathways in cancer. Understanding their regulation may inform the development of therapies to impair lung tumor metastasis.

MiRNA-300 suppresses proliferation, migration and invasion of non-small cell lung cancer via targeting ETS1.

The study demonstrated that LINC00483 facilitates the proliferation, migration and invasion of lung adenocarcinoma cells by acting as a sponge for miR-204-3p, which in turn regulates ETS1.

MicroRNA-365 inhibits the progression of lung adenocarcinoma through targeting ETS1 and inactivating AKT/mTOR pathway.