lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

2052

PubMed (Gene Name)

Literature evidence

12915882 (EPHX1)

polymorphisms in microsomal epoxide hydrolase associated with lung cancer risk

15640939 (EPHX1)

The slow 113His EPHX1 allele tends to be more frequent among the patients with lung cancer than in normal controls

17273734 (EPHX1)

the expression level of mEH is as important as genetic polymorphism in non-small cell lung cancer; could be involved in drug resistance and prognosis of patients

17767854 (EPHX1)

The interaction between the polymorphisms of mEH gene and the indoor air pollution plays an important role in the carcinogenesis of lung.

18298806 (EPHX1)

C-Allele of EPHX1(His113Tyr)plays a protective role in early onset lung cancer susceptibility

18571762 (EPHX1)

analysis of lung cancer in subjects under age 45 supports the hypothesis that EPHX1 polymorphisms may have a role in cancer susceptibility in this age group.

20091863 (EPHX1)

Modifying effect of EPHX1 polymorphisms on the risk of early-onset lung cancer.M

21302624 (EPHX1)

Data suggest that the exon 3 Tyr113His and exon 4 His139Arg polymorphisms of EPHXI may be associated with a increased risk of lung cancer and a worse prognosis.

21445251 (EPHX1)

Putative low EPHX1 enzyme activity may have a potential protective effect on tobacco-related carcinogenesis of lung and UADT cancers, whereas putative high EPHX1 activity may have a harmful effect

21649467 (EPHX1)

EPHX1 polymorphism is associated with lung cancer susceptibility in Indian population.

23055191 (EPHX1)

Meta-analyses of available data supported the concept of EPHX1 A139G polymorphism as a genetic susceptibility factor for lung cancer

23378225 (EPHX1)

Microsomal epoxide hydrolase 1 T113C polymorphism is associated with lung cancer.

23928928 (EPHX1)

Results suggest that Exons 3 and 4 polymorphisms of the mEH gene may contribute to lung cancer susceptibility through disturbed antioxidant balance.

24852519 (EPHX1)

No clear effect is evident for EPHX1 polymorphisms for different radon concentrations on the risk of lung cancer.

25222243 (EPHX1)

the EPHX1 Tyr113His polymorphism may be a risk factor for lung cancer in Asians, whereas it may be a decreased risk factor among Caucasians. However, this polymorphism was not found to be associated with breast cancer.

25312477 (EPHX1)

the genetic associations exist between mEH polymorphisms and lung cancer susceptibility in Asian populations

26216302 (EPHX1)

Studies suggest that the presence of microsomal epoxide hydrolase 1 (EPHX1) single nucleotide polymorphisms (SNPs) may significantly affect the risk of lung, upper aerodigestive tract, breast, bladder, and ovarian carcinomas.