There is a negative corelation between the expression of HIF-2alpha and OCT-4 and the prognosis of non-small cell lung cancer.

Our results suggest that HIF-2alpha may represent a more aggressive phenotype in small cell lung cancer

Elevations of HIF-2alpha expression are associated with non-small cell lung cancer.

the EPAS1 rs4953354 may be a potentially susceptible marker for development of lung adenocarcinoma, especially in female never-smokers

HIF-2alpha is highly expressed in lung cancer stem cells, which may lead to radioresistance. In conclusion, HIF-2alpha is a potential prognostic marker for lung cancer

both FDG uptake and HIF-2alpha expression may represent a more aggressive phenotype and that HIF-2alpha may play a more important role than HIF-1alpha in the uptake of FDG in lung adenocarcinoma

MicroRNA-383 is a tumor suppressor in human lung cancer by inhibiting EPAS1, both of which could serve as potential therapeutic targets in the treatment of lung cancer.

Our results indicate that HPV16 E6/E7 indirectly upregulated the expression of VEGF by inhibition of liver kinase B1 expression and upregulation of hypoxia-inducible factor 2alpha expression,thus propose a human papillomavirus-liver kinase B1-hypoxia-inducible factor 2A-vascular endothelial growth factor axis for the tumorigenesis of lung cancer

EPAS1 promotes peritoneal carcinomatosis of non-small-cell lung cancer by enhancing mesothelial-mesenchymal transition.

HIF2alpha cooperates with RAS to promote lung tumorigenesis in mice.