Links to all GeneRIF Items | 1846 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 30475228 (Dusp4) | compound-heterozygous deletion of Dok2 and Dusp4 in mice resulted in lung tumorigenesis with short latency and high incidence, and that their co-deletion synergistically activated MAPK signaling and promoted cell proliferation. |
| 19525976 (DUSP4) | Results show that DUSP4 is involved in negative feedback control of EGFR signaling, and provide functional validation for its role as a growth suppressor in EGFR-mutant lung adenocarcinoma. |