lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

1789

PubMed (Gene Name)

Literature evidence

12208751 (DNMT3B)

The DNMT3B C46359T polymorphism is associated with promoter activity of a novel DNMT3B transcript, and associated with the risk of lung cancer in non-Hispanic whites.

15528220 (DNMT3B)

The DNMT3B -283T > C polymorphism influences DNMT3B expression, thus contributing to the genetic susceptibility to lung cancer.

16004934 (DNMT3B)

involvement of HPV infection in nonsmoking female lung tumorigenesis may be mediated, at least to a certain extent, through the increase of DNMT3b protein expression to cause p16INK4a promoter hypermethylation

16773201 (DNMT3B)

DeltaDNMT3B is the predominant form of DNMT3B in non-small cell lung cancer.

16951144 (DNMT3B)

expression of DNMT3B variants is common in nsn-small cell lung carcinoma and may play an important role in the development of promoter methylation.

17369845 (DNMT3B)

tobacco exposure induces the abnormal expression of SNCG in lung cancer cells through downregulation of DNMT3B

17890317 (DNMT3B)

expression of microRNA is inversely correlated with DNMT3B in non-small cell lung cancer.

19024105 (DNMT3B)

role of deltaDNMT3B4/2 in regulating RASSF1A promoter-specific DNA methylation in non-small cell lung cancer.

24469050 (DNMT3B)

Our results identify a key role for DNMT3b in the earliest stages of initiation and provide a comprehensive catalog of genes targeted for silencing by this methyltransferase in non-small-cell lung cancer.

25122426 (DNMT3B)

We reveal a new mechanism that FOXO3a transcriptionally represses DNMT3B expression and this regulation can be attenuated by MDM2 overexpression in human lung cancer model.

26629529 (DNMT3B)

Our results demonstrate DNMT3B4-del as a critical factor in developing aberrant DNA methylation patterns during lung tumorigenesis and suggest that DNMT3B4-del may be a target for lung cancer prevention.

27876061 (DNMT3B)

149C>T and -2437T>A DNMT3B polymorphisms are not correlated with lung cancer risk among Chinese population nor the haplotype of them.

29027179 (DNMT3B)

These results provided evidence that the DNMT3B -283T>C polymorphism might significantly contribute to the lung cancer risk in the Asian population, but not the gastric cancer risk in the Chinese population.

29332452 (DNMT3B)

The following meta-analysis involved only Chinese population and further confirmed the significant association of -579G>T with gastric cancer but not lung cancer and suggested no significant association between -149C>T and risk of lung or gastric cancer. Collectively, DNMT3B -579G>T polymorphism is associated with gastric cancer risk in Chinese population