Links to all GeneRIF Items | 1576 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 14515059 (CYP3A4) | The CYP3A4*1B allele is associated with small cell lung cancers |
| 15731117 (CYP3A4) | transcriptional activation of ZNF185 and CYP3A4 is mediated by direct association of BRG1 with their promoters and a decreased level of ZNF185 is a common feature of lung tumours |
| 21963990 (CYP3A4) | CYP3A4 expression alters protein secretion in human hepatocarcinoma cells, human mammary epithelial cells and C10 mouse lung cells through reactive oxygen species production. |
| 24085358 (CYP3A4) | Individual carrying at least one variant allele of CYP3A4*1B (CYP3A4*1A/1B + *1B/1B) has a 3.35 times more risk (OR = 3.35, 95 % Cl = 0.34-32.71, p = 0.271) for developing lung cancer |
| 28444958 (CYP3A4) | Results suggest that CYP4503A4/1A2 phenotyping is unlikely to substitute therapeutic drug monitoring of erlotinib in patients with advanced non-small cell lung cancer. |