lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

1545

PubMed (Gene Name)

Literature evidence

11955671 (CYP1B1)

airborne particulates generated during the frying of beef, fish and pork can induce carcinogen-metabolizing CYP1B1 in the human lung-derived cell line

16051642 (CYP1B1)

CYP1B1 Leu(432)Val alone and in combination with Phase II enzyme polymorphisms was more strongly associated with increased lung cancer susceptibility among those with at least some household environmental tobacco smoke exposure

17200336 (CYP1B1)

AhR overexpression up-regulates the expression of CYP1B1 in the early stage of lung adenocarcinoma

17980933 (CYP1B1)

CYP1B1, CYP1A1, MPO, and GSTP1 polymorphisms and lung cancer risk in never-smoking Korean women.

18573508 (CYP1B1)

Genotype polymorphic combinations of CYP1B1Ala119Ser and CYP1B1Leu432Val with GSTM1 is associated with lung cancer.

19730035 (CYP1B1)

Genetic polymorphism in CYP1B1 gene is not associated with cardiovascular disease, pulmonary disease, and cancer.

20395011 (CYP1B1)

genetic polymorphism contributes to lung cancer risk

21674184 (CYP1B1)

CYP1B1 432GG, 119TT and 48GG genotypes are low-penetrance risk factors for developing lung cancer.

22272893 (CYP1B1)

summary of present knowledge of genetic variation in cytochrome P450 1B1 and 2C9 genes and risk of tobacco-related cancer, estrogen-related cancer, chronic obstructive pulmonary disease, and ischemic vascular disease [REVIEW]

24989113 (CYP1B1)

Meta-analysis/Review: CYP1B1 Leu432Val polymorphism acts as a risk factor for the carcinogenesis of lung cancer.

25504507 (CYP1B1)

CYP1B1 4326C>G polymorphism emerged as possible prognostic/predictive marker of activity and efficacy of docetaxel in non-small cell lung cancer patients.

26283052 (CYP1B1)

CYP1B1 Leu432Val is associated with increased lung cancer susceptibility among Caucasians, and there is an interaction between CYP1B1 Leu432Val polymorphism and smoking, and Asn453- Ser and Ala119Ser may be not associated with lung cancer risk.

26990437 (CYP1B1)

Utilizing a mouse model, null for Cyp1b1 and expressing human CYP1B1, the study tested the hypothesis that hCYP1B1 is important for dibenzo[def,p]chrysene (DBC) transplacental carcinogenesis. hCYP1B1 genotype did not impact lung tumor multiplicity, but tended to enhance incidence compared to Cyp1b1 wild-type mice (P = 0.07).

27495872 (CYP1B1)

MicroRNA-187-5p suppresses cancer cell progression in non-small cell lung cancer through down-regulation of CYP1B1.

27922681 (CYP1B1)

High CYP1B1 expression is associated with cisplatin-resistance in non-small cell lung cancer.

28858732 (CYP1B1)

the CYP1B1 status in tissues from 76 patients diagnosed with non-small cell lung cancer, was investigated.

29938532 (CYP1B1)

CYP1B1 single nucleotide polymorphisms association with lung cancer susceptibility in Polish smokers.