lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

1500

PubMed (Gene Name)

Literature evidence

19150613 (CTNND1)

p120ctn isoforms 1A and 3A differently regulated the adhesive, proliferative, and invasive properties of lung cancer cells through distinct mechanisms.

19154401 (CTNND1)

p120-catenin gene knockdown enhances the metastasis of lung cancer cells

19763914 (CTNND1)

In lung cancer, p120ctn isoform 1 over-expression correlated positively with lymph node metastasis, poor differentiation, histological type, & high TNM stage. expression in metastases was always higher than in the primary tumor.

20232357 (CTNND1)

Knockdown of HDPR1 gene enhanced the invasive ability of lung cancer cells, which was dependent on p120ctn and independent of beta-catenin

20460685 (CTNND1)

Reduced p120ctn promoter activity, protein level, and mRNA message is found in lung cancer cells compared with noncancerous immortalized lung epithelial cells.

21070476 (CTNND1)

Increased delta-catenin expression is critical for maintenance of the malignant phenotype of lung cancer, making delta-catenin a candidate target protein for future cancer therapeutics.

21336985 (CTNND1)

The data provide evidence for the role of c-Crk proto-oncogene in transcriptional repression of p120ctn that further clarifies the mechanism by which this biochemical signal promotes metastasis in non-small cell lung cancer.

21468542 (CTNND1)

p120-catenin isoform 3 regulates the nuclear export of Kaiso and promotes invasion in lung cancer cells via a phosphorylation-dependent mechanism.

22276175 (CTNND1)

Results suggest that p120ctn isoforms 1 and 3 up-regulate cyclin D1, and thereby cyclin E, resulting in the promotion of cell proliferation and cell cycle progression in lung cancer cells.

23839039 (CTNND1)

Overexpression of NLBP promotes the cell proliferation of lung adenocarcinoma through interacting with p120ctn.

24498333 (CTNND1)

Data indicate that Kaiso protein participates in the regulation of beta-catenin mRNA expression by interacting with p120-catenin in the lung cancer cell lines.

30841025 (CTNND1)

This study was aimed to explore if lncRNA MALAT1 would modify chemo-resistance of non-small cell lung cancer (NSCLC) cells by regulating miR-197-3p and p120 catenin (p120-ctn).

23733751 (Ctnnd1)

we show that somatic loss of p120-catenin (p120) in a conditional mouse model of noninvasive mammary carcinoma results in formation of stromal-dense tumors that resemble human metaplastic breast cancer and metastasize to lungs and lymph nodes