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Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

1490

PubMed (Gene Name)

Literature evidence

14996858 (CTGF)

CTGF inhibits metastasis and invasion of human lung adenocarcinoma by a CRMP-1-dependent mechanism.

16877704 (CTGF)

CTGF may behave as a secreted tumor suppressor protein in the normal lung, and its expression is suppressed in many NSCLCs.

17579708 (CTGF)

Downregulation of the CTGF is associated with lung cancer.

19069651 (CTGF)

CTGF and WISP-1 could play an important role in the progression of primary lung cancers by either individual gene itself or cointeraction.

27393180 (CTGF)

Decreased expression of CTGF is a common feature in Non Small Cell lung cancer; however, it can be restored by the chromatin-modifying agents such as 5-dAzaC or TSA and consequently restrain cancer development.