CSF1, EGFR, and CA IX have roles in increasing survival in early-stage squamous cell carcinoma of the lung

high expression correlates with shorter metastasis-free survival in non-small-cell lung cancer patients

miR-1207-5p and CSF1 expression levels and their relationship with lung cancer survival and metastasis status were assayed by means of a lung cancer tissue microarray.

Data showed that single expression of M-CSF or IL-34 can be observed in lung cancer tissues and correlated with poor survival. Additionally, their high co-expression correlates with disease stages and poor survival. Thus, evaluating the expression of both M-CSF and IL-34 may help to estimate disease progression and malignant degree in lung cancer patients.

Oct4 promotes M2 macrophage polarization through upregulation of macrophage colony-stimulating factor in lung cancer.

in lung cancer bone metastasis, regulates tumor cell proliferation, cancer stem-like cells, and osteoclastic bone resorption