lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

1316

PubMed (Gene Name)

Literature evidence

17223258 (KLF6)

our results suggest a potential involvement of KLF6 polymorphisms in lung cancer risk

18250346 (KLF6)

Increased expression of KLF6-SV1 is associated with decreased survival in patients with lung adenocarcinoma.

19328586 (KLF6)

increased expression is associated with acquired chemotherapy resistance in lung adenocarcinoma cells

30590988 (KLF6)

Study found that overexpression of Kruppel like factor 6 splice variant 1 (KLF6-SV1) promoted the expression of TWIST1, and up-regulation of TWIST1 expression might promote the infiltration of M2 macrophages by up-regulating CCL2, thereby promoting the involvement of epithelial-mesenchymal transition in the metastasis of lung cancer cells.