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Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

114757

PubMed (Gene Name)

Literature evidence

21684245 (Cygb)

Cygb deficiency induces susceptibility to cancer development in the liver and lungs of mice exposed to N,N-diethylnitrosamine

16698880 (CYGB)

Results provide the first evidence to suggest the implication of CYGB in the pathogenesis of non-small cell lung cancer.

23591990 (CYGB)

Results show that CYGB revealed tumor Suppressor Gene properties in normoxia but promoted tumourigenic potential of the cells exposed to stress, suggesting a bimodal function in lung tumourigenesis.

26096935 (CYGB)

DeltaNp63-CYGB axis is also present in lung and breast cancer cell lines, indicating that CYGB-mediated ROS-scavenging activity may also have a role in epithelial tumours