Links to all GeneRIF Items | 11334 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 11593436 (TUSC2) | Overexpression of candidate tumor suppressor geneFUS1 isolated from the 3p21.3 homozygous deletionregion leads to G1 arrest and growth inhibition oflung cancer cells. |
| 15126327 (TUSC2) | Myristoylation is required for Fus1-mediated tumor-suppressing activity and suggest a novel mechanism for the inactivation of tumor suppressors in lung cancer. |
| 18172250 (TUSC2) | FUS1 gene and Fus1 protein abnormalities could be used to develop new strategies for molecular cancer therapy for a significant subset of lung tumors. |
| 19671678 (TUSC2) | These results suggest that the three miRNAs are negative regulators of Fus1 expression in lung cancers. |
| 26053020 (TUSC2) | The therapeutic activity of TUSC2 could extend the use of erlotinib to lung cancer patients with wildtype EGFR. |