Links to all GeneRIF Items | 11315 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 21670963 (PARK7) | DJ-1 expression was found to be significantly correlated with lymphatic metastasis of non-small cell lung cancer. |
| 21943684 (PARK7) | Nuclear factor erythroid-derived 2-like 2 and its stabilizing protein DJ1 affect the prognosis of patients with lung cancer by inducing an elevated stress response to oxidative damage. |
| 26125099 (PARK7) | DJ-1 is increased in elderly lung cancer patients with malignant pleural effusions and may have a role in redox regulation |
| 26245297 (PARK7) | High expression of PARK7 might lead to the occurrence of non-small-cell lung cancer. |
| 26334622 (PARK7) | Serum levels of thioredoxin and DJ-1 were significantly higher in non-small cell lung cancer patients; therefore, these may be utilized as novel diagnostic and prognostic biomarkers for non-small cell lung cancer |
| 28580701 (PARK7) | Downregulation of DJ-1 using DJ-1-siRNA in H69AR cells sensitized cancer cells to chemotherapeutic drugs through increasing drug-induced cell apoptosis accompanied with G0-G1 phase arrest. These findings suggest DJ-1 may serve as a potential biomarker for chemoresistance and prognostic factor for patients with small-cell lung cancer (SCLC). |
| 28653888 (PARK7) | DJ-1 was highly expressed in the early stage of lung cancer, and its expression was significantly decreased after metastasis. Therefore, DJ-1 may be a potential biomarker for the early diagnosis and monitoring of lung cancer metastasis |