Links to all GeneRIF Items | 10891 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 24583643 (PPARGC1A) | Loss of RIP1 in lung cancer cells suppresses peroxisome proliferator-activated receptor gamma coactivator-1alpha expression. |
| 29192176 (PPARGC1A) | PGC-1alpha mRNA levels inversely correlate with GAPDH/MT-CO1 ratio. PGC-1alpha and GAPDH/MT-CO1 levels could be used to predict patient response to treatments based on targeting glucose metabolism on lung cancer. |
| 30880247 (PPARGC1A) | These results describe a new cisplatin resistance mechanism in Non-Small Cell lung cancer based on a metabolic reprogramming that is therapeutically exploitable through PGC-1a downregulation or OXPHOS inhibitors. |
| 31713888 (PPARGC1A) | The present study found two genetic variants (i.e., HDAC2 rs13213007 G>A and PPARGC1A rs60571065 T>A) in the CREB-binding protein pathway gene-set to be significantly associated with survival of patients with non-small-cell lung cancer. |