Links to all GeneRIF Items | 10738 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 25481043 (RFPL3) | These results demonstrate that RFPL3 is an important cellular factor which promotes lung cancer growth by activating hTERT expression |
| 26318425 (RFPL3) | RFPL3 and CBP have roles in upregulating hTERT activity and promoting lung cancer growth |
| 29749533 (RFPL3) | EGF significantly upregulated RFPL3 and hTERT protein levels in the nonsmall cell lung cancer cells. RFPL3 and hTERT proteins upregulation by EGF were attenuated by pretreatment with AG1478 and erlotinib. EGF promoted proliferation and inhibited apoptosis; PD98059 decreased RFPL3 and hTERT protein expression; and RFPL3 overexpression increased the expression of hTERT and related MEKpathway proteins |