lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

10642

PubMed (Gene Name)

Literature evidence

17255263 (IGF2BP1)

IMP-1 expression is likely to play important roles in lung cancer development and progression

30353165 (IGF2BP1)

Results found that IGF2BP1 was significantly activated in lung adenocarcinoma (LUAD) patients. Also, the expression of IGF2BP1 was significantly higher in LUAD patients with LIN28B-AS1 activation than other patients. LIN28B-AS1 alters the LIN28B mRNA stability by directly interacting with IGF2BP1.

30371874 (IGF2BP1)

35 SRF/IGF2BP1-dependent genes showing conserved association with SRF and IGF2BP1 expression indicate a poor overall survival probability in ovarian, liver and lung cancer. In conclusion, these findings identify the SRF/IGF2BP1-, miRNome- and m6A-dependent control of gene expression as a conserved oncogenic driver network in cancer.

31085008 (IGF2BP1)

We demonstrate that low IGF2BP1 and FOXM1 expression can serve as a potential factor for the clinical diagnosis and prognosis of lung adenocarcinoma

32926844 (IGF2BP1)

IGF2BP1 silencing inhibits proliferation and induces apoptosis of high glucose-induced non-small cell lung cancer cells by regulating Netrin-1.

33268793 (IGF2BP1)

A novel circular RNA, circXPO1, promotes lung adenocarcinoma progression by interacting with IGF2BP1.

33436560 (IGF2BP1)

circNDUFB2 inhibits non-small cell lung cancer progression via destabilizing IGF2BPs and activating anti-tumor immunity.